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Text File  |  1987-10-07  |  541b  |  16 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, METHYLDOPA DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (PROLONGED HYPO-
  4.          TENSION, HEPATITIS).
  5.  
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE ADJUSTED
  7.          BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.  
  9.                      CREATININE
  10.                       CLEARANCE        DOSAGE INTERVAL
  11.                      (ML/MINUTE)
  12.  
  13.                         10-50          9 to 18 hours
  14.                          <10           12 to 24 hours
  15.  
  16.